Nattokinase: The Complete Guide to This Traditional Fermented Enzyme

Nattokinase: The Complete Guide to This Traditional Fermented Enzyme

Nattokinase: The Complete 2025 Guide to This Fermented Soy Enzyme

Nattokinase has become one of the most talked-about fermented-food enzymes in modern nutrition. Extracted from natto, a traditional Japanese fermented soybean dish, this natural enzyme has gained attention for its clean origin, traditional background, and increasing use in enzyme-support supplements.

This guide explains what nattokinase is, how it’s made, and how to choose a high-quality supplement.

If you’re interested in trying a clean, organic formula, explore our product here:
Nattokinase Organic 60 Capsules

What Is Nattokinase?

Nattokinase is a naturally occurring serine protease enzyme produced when soybeans are fermented with Bacillus subtilis natto. It is part of the proteolytic enzyme family, known for breaking down proteins during digestion.

Nattokinase is:

  • Derived from fermented soybeans

  • Standardised and purified for supplement use

  • Vegan-friendly in most formulas

  • Popular among consumers who prefer fermented-food–based ingredients

The History of Natto & Nattokinase

Natto has been part of Japanese cuisine for over a millennium. It is known for:

  • Its strong, distinctive flavour

  • Sticky, stringy texture

  • High levels of vitamin K2, plant proteins, probiotics, and natural enzymes

Nattokinase was identified in the 1980s during research exploring natto’s enzyme activity. Since then, it has become widely used in dietary supplements.

How Nattokinase Is Made

Understanding the production process helps identify superior products.

1. Soybean Preparation

Non-GMO soybeans are soaked, steamed, and prepared for fermentation.

2. Fermentation with Bacillus subtilis natto

This bacterium produces nattokinase as it naturally breaks down the soybeans.

3. Enzyme Extraction

The nattokinase enzyme is separated, purified, and filtered.

4. Standardisation in FU (Fibrinolytic Units)

High-quality products display enzyme activity measured in FU to ensure consistency.

5. Encapsulation Under GMP Standards

Final formulas are produced in GMP-certified facilities for quality and accuracy.

Why Nattokinase Is Growing in Popularity

Several wellness trends contribute to its rising demand:

  • Increased interest in fermented-food ingredients

  • Growing use of enzyme-based supplements

  • Preference for plant-based, vegan-friendly options

  • Convenience compared to consuming natto itself

How to Choose a High-Quality Nattokinase Supplement

When comparing products, consider the following:

1. FU Strength (Enzyme Activity Level)

Common strengths include:

  • 2,000 FU

  • 4,000 FU

  • 6,000 FU

FU (Fibrinolytic Units) indicates enzyme potency per capsule.

2. Non-GMO Soy Source

Premium nattokinase typically uses non-GMO soybeans.

3. GMP Manufacturing

Ensures consistent production standards and quality control.

4. Capsule Type

Choose plant-based cellulose capsules if you prefer a vegan-friendly product.

5. Minimal Additives

Look for clean formulas containing only the enzyme, capsule shell, and essential stabilisers.

For a clean, organic and standardised option, see:
Nattokinase Organic 60 Capsules

How Nattokinase Is Commonly Used

Consumers often include nattokinase in:

  • Daily wellness routines

  • Fermented-food–inspired nutrition programs

  • Enzyme-support supplement stacks

  • Vegan and plant-based supplement collections

Always follow the guidance on your supplement label.

Nattokinase vs Natto: Understanding the Difference

Natto (Food)

  • Fermented whole soybeans

  • Strong flavour profile

  • Contains vitamin K2, fibre, probiotics, and natural enzymes

Nattokinase (Supplement)

  • Purified enzyme extracted from natto

  • Higher enzyme concentration

  • Does not contain vitamin K2

  • Neutral flavour, easy-to-take capsules

Frequently Asked Questions

Does nattokinase contain vitamin K2?
No. Natto contains vitamin K2, but the purified enzyme does not.

Is nattokinase vegan?
Most formulas are vegan-friendly if they use cellulose capsules.

Is nattokinase the same as natto?
No—natto is the whole fermented food; nattokinase is the isolated enzyme.

What does “FU” mean?
FU stands for Fibrinolytic Units, a measurement of enzyme activity.

Does nattokinase contain soy?
Yes, as it is derived from fermented soybeans.

Shop Nattokinase

Looking for a clean, organic nattokinase formula?
Explore:
Nattokinase Organic 60 Capsules

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